Antibodies to parvovirus, distemper virus and adenovirus conferred to household dogs using commercial combination vaccines containing Leptospira bacterin

• Published in: Veterinary record Vol. 167; no. 24; pp. 931 - 934
• Main Authors: Taguchi, M., Namikawa, K., Maruo, T., Lynch, J., Sahara, H.
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Limited 11.12.2010; Blackwell Publishing Ltd
• Subjects: Adenoviridae Infections - prevention & control; Adenoviridae Infections - veterinary; Adenovirus; Adenoviruses, Canine - immunology; Age groups; Animal vaccines; Animals; Antibodies, Viral - blood; Antigens; Antigens, Viral - blood; Bacteria; Bacterial Vaccines; Canine distemper virus; Canine parvovirus; Distemper - prevention & control; Distemper Virus, Canine - immunology; Dog Diseases - prevention & control; Dogs; Female; Immunization; Infections; Leptospira; Leptospira - immunology; Male; Mutation; Parvoviridae Infections - prevention & control; Parvoviridae Infections - veterinary; Parvovirus; Parvovirus, Canine - immunology; Studies; Vaccines, Combined; Viral Vaccines - immunology; Viruses
• ISSN: 0042-4900; 2042-7670
• DOI: 10.1136/vr.c6225

To examine how the inclusion (+) or exclusion (–) of inactivated Leptospira antigens in a vaccine for canine parvovirus type 2 (CPV-2), canine distemper virus (CDV) and canine adenovirus type 2 (CAdV-2) affects antibody titres to CPV-2, CDV and CAdV-1 antigens, household dogs were vaccinated with commercially available vaccines from one of three manufacturers. CPV-2, CDV and CAdV-1 antibody titres were measured 11 to 13 months later and compared within three different age groups and three different bodyweight groups. There were significant differences between CPV-2 antibody titres in dogs vaccinated with (+) vaccine and those vaccinated with (–) vaccine for two products in the two-year-old group and for one product in the greater than seven-year-old group; no significant differences were seen that could be attributed to bodyweight. No differences in CDV antibody titres were observed within age groups, but a significant difference was seen in the 11 to 20 kg weight group for one product. Significant differences in CAdV-1 antibody titres were seen for one product in both the two-year-old group and the ≤10 kg weight group.