Prognostic value of ECG monitor findings in COVID-19

• Published in: Open heart Vol. 10; no. 2; p. e002404
• Main Authors: Hashimoto, Hidenobu, Hiyoshi, Yasunaga, Kabuki, Takayuki, Sasaki, Hideto, Toda, Mikihito
• Format: Journal Article
• Language: English
• Published: London British Cardiovascular Society 01.11.2023; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Anticoagulants; Arrhythmias and sudden death; atrial fibrillation; Body mass index; Cardiac arrhythmia; Cardiovascular disease; COVID-19; Diabetes; electrocardiography; Heart failure; Heart rate; Hospitalization; Hospitals; Hypertension; Infections; Ischemia; Kidney diseases; Lung diseases; Medical records; Mortality; Pandemics; Patients; Pneumonia; Ventilators
• ISSN: 2053-3624; 2398-595X; 2053-3624
• DOI: 10.1136/openhrt-2023-002404

AimsCOVID-19 can cause severe illness and multiorgan dysfunction. Acute myocardial damage has been detected in a significant portion of patients with COVID-19; therefore, several studies have reported that electrocardiographic findings could be used to evaluate the severalty of COVID-19. However, performing standard ECG for each patient hospitalised with COVID-19 can increase the level of exposure to COVID-19 among medical staff. Therefore, this study aimed to investigate the prognostic value of continuous electrocardiographic monitor findings in patients with COVID-19.MethodsAmong 1612 consecutive patients with COVID-19 who were admitted to our hospital between August 2021 and May 2022, we identified 96 (76±4 years) patients who underwent electrocardiographic monitor during hospitalisation. All electrocardiographic monitors were analysed by two independent cardiologists blinded to the clinical data of the patients. The endpoint was defined as the occurrence of all-cause mortality related to COVID-19. The event data were retrospectively gathered from the patients’ medical records. A multivariate Cox model was used to assess whether these electrocardiographic monitor findings and clinical data were associated with in-hospital mortality.ResultsDuring a mean hospitalisation period of 22.8±3.2 days, in-hospital mortality occurred in 17 (18%) patients. Atrial fibrillation (HR: 3.95, 95% CI: 1.39 to 11.21) and lung disease complications (HR: 2.91, 95% CI: 1.06 to 7.98) were significant prognostic factors for death in multivariate analysis. Compared with the non-complicated lung disease and non-atrial fibrillation group, the risk of mortality was significantly higher in the lung disease complication and atrial fibrillation group in the multivariate Cox proportional model (HR: 8.37, 95% CI: 1.69 to 41.30, p=0.009).ConclusionsThe simple method of ECG monitor could adequately detect atrial fibrillation. This study demonstrated that atrial fibrillation complicated with lung disease, could have potential prognostic value among patients with COVID-19.