Gastric dysplasia causing gastric outlet obstruction

• Published in: BMJ case reports Vol. 14; no. 7; p. e243208
• Main Authors: Kumar, Rahul, Ilahi, Ipsit, Prajapati, Tripti, Garg, Pankaj Kumar
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 27.07.2021; BMJ Publishing Group
• Subjects: 20th century; Abdomen; Anemia; Antigens; Ascites; Case Report; Case reports; Endoscopy; English literature; Female; Gallbladder; Gastric cancer; Gastric Outlet Obstruction - diagnostic imaging; Gastric Outlet Obstruction - etiology; Gastric Outlet Obstruction - surgery; Gastroenterostomy; Gastrointestinal surgery; Humans; Medical imaging; Patients; Physicians; Stomach Neoplasms - complications; Stomach Neoplasms - surgery; Surveillance; Tuberculosis; Ulcers; Vomiting; India; gastric cancer; gastrointestinal surgery; general surgery
• ISSN: 1757-790X; 1757-790X
• DOI: 10.1136/bcr-2021-243208

Gastric dysplasia signifies the presence of atypical cells in the gastric mucosa, which have not invaded beyond the lamina propria, and it rarely leads to tissue growth large enough to cause gastric outlet obstruction (GOO) to the gastric contents. However, GOO is commonly observed as a first clinical manifestation of advanced invasive gastric cancer in developing countries where patients seek medical care late. The present case highlights the treatment journey of a young woman who presented to us with features of GOO. Her endoscopic and radiological findings revealed a nodular gastric antral thickening causing GOO. An endoscopic biopsy showed features of dysplasia. She underwent distal gastrectomy following discussion in a multidisciplinary tumour board. Histopathological examination of the gastrectomy specimen confirmed dysplasia without any invasion beyond lamina. To the best of our knowledge, this is perhaps the first report of dysplasia of the stomach presenting as GOO.