Salvage immunotherapy for fulminant pseudomembranous colitis

• Published in: BMJ case reports Vol. 2013; p. bcr2012008786
• Main Authors: Abdulaziz, Salman, Abou-Shala, Nabil, Al-Tarifi, Ashraf, Amin, Rashid
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 20.02.2013; BMJ Publishing Group
• Series: Images in
• Subjects: Clostridium difficile - isolation & purification; Diagnosis, Differential; Diarrhea; Enterocolitis, Pseudomembranous - diagnosis; Enterocolitis, Pseudomembranous - therapy; Humans; Images In; Immunoglobulins, Intravenous - therapeutic use; Immunotherapy - methods; Infections; Inflammatory bowel disease; Male; Middle Aged; Middle East; Salvage; Salvage Therapy - methods; Sigmoidoscopy - methods; Tomography, X-Ray Computed - methods
• ISSN: 1757-790X; 1757-790X
• DOI: 10.1136/bcr-2013-008786

Table 1 Complete blood count Normal range Results White cell count 3.9-11x109/l 48.2x109/l Haemoglobin 135-180 g/l 73 Platelet 155-435x109/l 443 Renal chemistry - - Blood urea nitrogen (BUN) 2.5-7.5 mmol/l 14.0 Creatine 64-115 [mu]mol/l 235 Sodium 135-147 mmol/l 130 Potassium 3.5-5 mmol/l 4.6 Chloride 98-111 mmol/l 94 Bicarbonate 22-31 mmol/l 18 Magnesium 0.7-1 mmol/l 0.85 Ionised calcium 1.13-1.32 mmol/l 0.76 Phosphorus 0.7-1.45 mmol/l 2.56 Venous blood gas - - pH 7.30-7.40 7.30 Mixed venous oxygen saturation (SVO2) 60-80% 60% Lactic acid 0.05-2 mmol/l 4.0 Other blood chemistries - - Procalcitonin <0.5 ng/ml 3.21 Albumin 32-48 g/l 27 Billirubin 0-21 [mu]mol/l 197 Early goal-directed therapy was initiated by aggressive fluid resuscitation, packed red cells transfusion and administering dopamine.