Recovery from blindness following accidental quinine overdose

Other than mild bilateral sensorineural hearing loss, the remainder of the neurological examination was normal. Quinine is believed to be directly toxic to the inner retina 2 and, while the natural history is of some recovery over days to weeks, residual visual field constriction is common and the v...

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Bibliographic Details
Published inPractical neurology Vol. 17; no. 6; pp. 469 - 471
Main Authors Hall, Hildegard Nikki, Tatham, Andrew J
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group LTD 01.12.2017
BMJ Publishing Group
Subjects
Drug overdose
Hearing loss
Image of the Moment
Toxicity
ophthalmology
neurotoxicology
quinine
cinchonism
visual loss
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Summary:Other than mild bilateral sensorineural hearing loss, the remainder of the neurological examination was normal. Quinine is believed to be directly toxic to the inner retina 2 and, while the natural history is of some recovery over days to weeks, residual visual field constriction is common and the vision may remain poor. [...]due to the arteriolar constriction seen in some, there have been several case reports of treatment to alleviate vasospasm with agents such as nimodipine. 1 While the retinal vasculature was unremarkable at initial assessment, we prescribed nimodipine based on the very poor level of vision and good safety profile of the medication.
ISSN:1474-7758
1474-7766
DOI:10.1136/practneurol-2017-001610