Febrile neutropenia and refeeding syndrome

We describe the management of a 4-year-old child with acute lymphoblastic leukaemia (ALL) who presented with febrile neutropenia, Cryptosporidium and subsequently developed refeeding syndrome. Febrile neutropenia is common and can be life-threatening and we highlight the identification of well low-r...

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Bibliographic Details
Published inArchives of disease in childhood. Education and practice edition Vol. 101; no. 6; pp. 296 - 303
Main Authors Jahn, H K, Barraclough, S, Currell, S, Tighe, M P
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group LTD 01.12.2016
Subjects
Anti-Bacterial Agents - therapeutic use
Child, Preschool
Cryptosporidiosis - drug therapy
Cryptosporidiosis - etiology
Febrile Neutropenia - etiology
Febrile Neutropenia - therapy
Humans
Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications
Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma - microbiology
Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy
Refeeding Syndrome - diagnosis
Refeeding Syndrome - etiology
Refeeding Syndrome - therapy
Risk Factors
Infectious Diseases
Oncology
General Paediatrics
Nutrition
Gastroenterology
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Summary:We describe the management of a 4-year-old child with acute lymphoblastic leukaemia (ALL) who presented with febrile neutropenia, Cryptosporidium and subsequently developed refeeding syndrome. Febrile neutropenia is common and can be life-threatening and we highlight the identification of well low-risk neutropenic children with resolved febrile illnesses suitable for early discharge. We also discuss the potential management strategies for Cryptosporidium. Refeeding syndrome is not common, but should be considered as a cause of acute inpatient deterioration and is a significant risk, with potential morbidity, in children who have undergone a period of catabolism. This article reviews the current literature and provides useful guidance on these issues.
Bibliography:ObjectType-Case Study-3
SourceType-Scholarly Journals-1
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ObjectType-Review-1
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ISSN:1743-0585
1743-0593
DOI:10.1136/archdischild-2015-308850