Spontaneous hyphaema and corneal haemorrhage as complications of microbial keratitis

• Published in: British journal of ophthalmology Vol. 71; no. 12; pp. 933 - 937
• Main Authors: Ormerod, L D, Egan, K M
• Format: Journal Article
• Language: English
• Published: BMA House, Tavistock Square, London, WC1H 9JR BMJ Publishing Group Ltd 01.12.1987; BMJ; BMJ Publishing Group LTD
• Subjects: Adult; Age Factors; Aged; Aged, 80 and over; Bacterial diseases; Bacterial diseases of the eye and orbit; Biological and medical sciences; Corneal Diseases - complications; Female; Hemorrhage - complications; Human bacterial diseases; Humans; Hyphema - complications; Infectious diseases; Keratitis - complications; Keratitis - etiology; Male; Medical sciences; Middle Aged; Pseudomonas Infections - complications; Sex Factors; Staphylococcal Infections - complications; Streptococcal Infections - complications; Infection; Human; Cornea; Eye disease; Keratitis; Hyphema; Bacteriosis; Complication; Hemorrhage; Anterior segment
• ISSN: 0007-1161; 1468-2079
• DOI: 10.1136/bjo.71.12.933

Hyphaema developed spontaneously in 16 of 458 patients with microbial keratitis treated at two centres on the East and West Coasts of the United States. Chronic corneal conditions were often present, and three cases had rubeosis iridis. Inflamed iris vessels were assumed to be the source of the haemorrhage. The hyphaemas tended to persist longer than is usual, particularly when coincident with a hypopyon. Recurrent hyphaemas are reported in two patients from outside this series. Spontaneous corneal haemorrhage was seen in three cases. Subepithelial bleeding settled rapidly, but a combined midstromal and pre-Descemet's haematoma cleared more slowly. Anterior segment bleeding was significantly associated with advanced age, female sex, infection with Gram-positive organisms, and hypopyon.