A 38 year old woman with hypotensive shock at the onset of menstruation: case outcome

A bone marrow biopsy sample showed normocellularity and multifocal aggregates of abnormal spindle shaped mast cells (figs 1 , 2 , and 3 ). Indolent systemic mastocytosis is distinguished from illnesses with similar clinical manifestations principally by the presence of raised serum tryptase concentr...

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Published inBMJ Vol. 338; no. mar09 1; p. b247
Main Authors Serrano Villar, Sergio, Perez-Somarriba, Juncal, Sainz Costa, Talia, Winstanley, Sarah, Santillana Lopez, Tomas, Escribano Mora, Luis, Orejas Gonzalez, Baltasar
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group LTD 09.03.2009
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Abstract A bone marrow biopsy sample showed normocellularity and multifocal aggregates of abnormal spindle shaped mast cells (figs 1 , 2 , and 3 ). Indolent systemic mastocytosis is distinguished from illnesses with similar clinical manifestations principally by the presence of raised serum tryptase concentrations and histological features, although these criteria are not always present in monoclonal mast cell activation syndrome.
AbstractList A bone marrow biopsy sample showed normocellularity and multifocal aggregates of abnormal spindle shaped mast cells (figs 1 , 2 , and 3 ). Indolent systemic mastocytosis is distinguished from illnesses with similar clinical manifestations principally by the presence of raised serum tryptase concentrations and histological features, although these criteria are not always present in monoclonal mast cell activation syndrome.
Author Winstanley, Sarah
Escribano Mora, Luis
Serrano Villar, Sergio
Sainz Costa, Talia
Perez-Somarriba, Juncal
Orejas Gonzalez, Baltasar
Santillana Lopez, Tomas
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  givenname: Baltasar
  surname: Orejas Gonzalez
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References 2007; 14
19273525 - BMJ. 2009;338:b846
19273526 - BMJ. 2009;338:b867
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  publication-title: Curr Med Chem
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Snippet A bone marrow biopsy sample showed normocellularity and multifocal aggregates of abnormal spindle shaped mast cells (figs 1 , 2 , and 3 ). Indolent systemic...
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SubjectTerms Adult
Allergies
Biomarkers - blood
Biopsy
Bone Marrow Cells - pathology
Bones
Female
Histamine
Humans
Hypotension - etiology
Mastocytosis, Systemic - complications
Mastocytosis, Systemic - pathology
Menstruation Disturbances - complications
Mutation
Shock - etiology
Tryptases - blood
Title A 38 year old woman with hypotensive shock at the onset of menstruation: case outcome
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