Isoniazid resistant TB and non-compliance

[...]it may develop in patients with proven compliance but in whom perfusion is inadequate; and, secondly, it may be the result of poor penetration by the medication such as in cases with abscesses and empyemas. 2, 3 This occurred in two of our patients with gross thickening and extensive calcificat...

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Published inThorax Vol. 59; no. 12; pp. 1098 - 1098; author reply 1099
Main Authors van Altena, R, van Soolingen, D, van der Werf, T S
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd and British Thoracic Society 01.12.2004
BMJ Publishing Group LTD
BMJ Group
Subjects
Antitubercular Agents - therapeutic use
Compliance
Drug resistance
Humans
isoniazid
Isoniazid - therapeutic use
Letter to the Editor
non-compliance
Patients
resistance
Treatment Refusal
Tuberculosis
Tuberculosis, Multidrug-Resistant - drug therapy
England
Netherlands
Wales
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Summary:[...]it may develop in patients with proven compliance but in whom perfusion is inadequate; and, secondly, it may be the result of poor penetration by the medication such as in cases with abscesses and empyemas. 2, 3 This occurred in two of our patients with gross thickening and extensive calcifications of the pleura who were infected with a susceptible M tuberculosis strain at the beginning of their treatment.
Bibliography:local:0591098
Correspondence to:
 Dr R van Altena
 Tuberculosis Unit, Beatrixoord, 9750 RA Haren, The Netherlands; r.van.altena@beatrixoord.nl
href:thoraxjnl-59-1098.pdf
PMID:15563712
ark:/67375/NVC-XW74C57W-9
istex:46DD8368E066168992D952C6C40168A9B84488F1
SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0040-6376
1468-3296