Diarylmethanols Synthesis by Nickel(II)-catalyzed Addition of Arylboronic Acids to Aryl Aldehydes
A practical procedure for the addition of arylboronic acids to aromatic aldehydes has been developed in the presence of NiCl2 (PPh3)(2) /1,3-bis-(2,6-diisopropylphenyl)imidazolium chloride (IPr.HCl) system with good yield. Generally, electron-rich and -neutral aryl aldehydes showed excellent reactiv...
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Published in | Letters in organic chemistry Vol. 17; no. 4; pp. 248 - 253 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
SHARJAH
Bentham Science Publ Ltd
01.01.2020
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Subjects | |
Online Access | Get more information |
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Summary: | A practical procedure for the addition of arylboronic acids to aromatic aldehydes has been developed in the presence of NiCl2 (PPh3)(2) /1,3-bis-(2,6-diisopropylphenyl)imidazolium chloride (IPr.HCl) system with good yield. Generally, electron-rich and -neutral aryl aldehydes showed excellent reactivity and provided desired products in high yields. This procedure will provide new way to the synthesis of diarylmethanols. |
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ISSN: | 1570-1786 1875-6255 |
DOI: | 10.2174/1570178616666190724124849 |