Diarylmethanols Synthesis by Nickel(II)-catalyzed Addition of Arylboronic Acids to Aryl Aldehydes

A practical procedure for the addition of arylboronic acids to aromatic aldehydes has been developed in the presence of NiCl2 (PPh3)(2) /1,3-bis-(2,6-diisopropylphenyl)imidazolium chloride (IPr.HCl) system with good yield. Generally, electron-rich and -neutral aryl aldehydes showed excellent reactiv...

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Bibliographic Details
Published inLetters in organic chemistry Vol. 17; no. 4; pp. 248 - 253
Main Authors Bie, Fusheng, Liu, Xuejing, Wang, Meng, Cui, Haizhu, Li, Tang, Ma, Jie, Cao, Han
Format Journal Article
LanguageEnglish
Published SHARJAH Bentham Science Publ Ltd 01.01.2020
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
nickel
catalysis
aromatic aldehydes
diarylmethanols
Arylboronic acids
addition
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Summary:A practical procedure for the addition of arylboronic acids to aromatic aldehydes has been developed in the presence of NiCl2 (PPh3)(2) /1,3-bis-(2,6-diisopropylphenyl)imidazolium chloride (IPr.HCl) system with good yield. Generally, electron-rich and -neutral aryl aldehydes showed excellent reactivity and provided desired products in high yields. This procedure will provide new way to the synthesis of diarylmethanols.
ISSN:1570-1786
1875-6255
DOI:10.2174/1570178616666190724124849