Renal nephroblastoma in a 10-month-old boxer

A 10-month-old male entire Boxer dog was presented for weight loss and abdominal distension with a large mass palpable within the abdomen. A unilateral nephrectomy was performed for a large renal nephroblastoma (30-cm diameter). The nephroblastoma was suspected stage I, with favourable histology (hu...

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Bibliographic Details
Published inVeterinary record case reports Vol. 8; no. 1
Main Author Richardson, Stephanie
Format Journal Article
LanguageEnglish
Published London British Veterinary Association 01.02.2020
Blackwell Publishing Ltd
Subjects
Abdomen
abdominal
Biochemistry
Biopsy
Blood
Case reports
Chemotherapy
clinical practice
companion animals
Dogs
Hematology
Hemoglobin
Histology
Histopathology
kidneys
Lymphatic system
Medical prognosis
Metastasis
neoplasia
Surgery
Tumors
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Summary:A 10-month-old male entire Boxer dog was presented for weight loss and abdominal distension with a large mass palpable within the abdomen. A unilateral nephrectomy was performed for a large renal nephroblastoma (30-cm diameter). The nephroblastoma was suspected stage I, with favourable histology (human Wilms tumour grading). No adjunctive chemotherapy was administered. The dog remains clinically well 27 months postnephrectomy. Renal nephroblastomas are rare canine neoplasms and reported survival time is variable. This case and other recent reports suggest that mean survival time may be longer than previously thought. Nephroblastomas should be considered as a differential in young dogs presenting with clinical signs of an abdominal space-occupying lesion. The absence of azotaemia on a biochemical profile does not preclude significant renal pathology.
ISSN:2052-6121
2052-6121
DOI:10.1136/vetreccr-2019-001026