Contraindications to the use of metformin

According to the United Kingdom prospective diabetes study, patients with type 2 diabetes randomised to intensive treatment with metformin, sulphonylurea, or insulin had similar degrees of glycaemic control and significantly reduced microvascular end points. 1 The study showed that the use of metfor...

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Bibliographic Details
Published inBMJ Vol. 326; no. 7379; pp. 4 - 5
Main Authors Jones, G C, Macklin, J P, Alexander, W D
Format Journal Article
LanguageEnglish
Published England British Medical Journal Publishing Group 04.01.2003
BMJ Publishing Group LTD
BMJ Publishing Group
EditionInternational edition
Subjects
Acidosis, Lactic - chemically induced
Contraindications
Diabetes
Diabetes Mellitus, Type 2 - drug therapy
Drug therapy
Heart attacks
Humans
Hypoglycemic Agents
Hypoxia
Insulin
Metformin
Mortality
Patients
Side effects
United Kingdom > UK
United Kingdom
UK
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Summary:According to the United Kingdom prospective diabetes study, patients with type 2 diabetes randomised to intensive treatment with metformin, sulphonylurea, or insulin had similar degrees of glycaemic control and significantly reduced microvascular end points. 1 The study showed that the use of metformin in obese patients reduced cardiovascular events.
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ISSN:0959-8138
0959-8146
1468-5833
1756-1833
DOI:10.1136/bmj.326.7379.4