Cardiovascular magnetic resonance with late gadolinium enhancement improves mortality prediction beyond echocardiography: a comparative effectiveness study

Background We tested the hypotheses that 1 ejection fraction (EF) assessed by cardiovascular magnetic resonance (CMR) is a stronger predictor of all cause mortality than EF assessed by echocardiography; and 2 CMR with late gadolinium enhancement (LGE) improves risk stratification over echocardiograp...

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Bibliographic Details
Published inJournal of cardiovascular magnetic resonance Vol. 14; no. S1; p. O34
Main Authors Schelbert, Erik B, Moguillansky, Diego, Wong, Timothy C
Format Journal Article
LanguageEnglish
Published New York BioMed Central 01.02.2012
BioMed Central Ltd
Elsevier
Subjects
Diabetes
Heart attacks
Mortality
Oral Presentation
Studies
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Summary:Background We tested the hypotheses that 1 ejection fraction (EF) assessed by cardiovascular magnetic resonance (CMR) is a stronger predictor of all cause mortality than EF assessed by echocardiography; and 2 CMR with late gadolinium enhancement (LGE) improves risk stratification over echocardiography EF in Cox regression models as determined by net reclassification improvement (NRI). Yet, if CMR with LGE improves risk stratification compared to echocardiography, then CMR would demonstrate a potential to optimize care through improved patient selection for interventions and more efficient allocation of healthcare resources.
ISSN:1532-429X
1097-6647
1532-429X
DOI:10.1186/1532-429X-14-S1-O34