Ineffectiveness and Comparative Pathogenicity of Attenuated Rabies Virus Vaccines for the Striped Skunk (Mephitis mephitis)
Three attenuated rabies virus vaccines (SAD-B19, ERA/BHK-21, AZA 2) were compared for efficacy and safety in the striped skunk (Mephitis mephitis) by the oral and intranasal routes. The SAD-B19 and ERA/BHK-21 vaccines were given orally; all three vaccines were given intranasally. Oral administration...
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Published in | Journal of wildlife diseases Vol. 26; no. 1; pp. 99 - 102 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Wildlife Disease Association
01.01.1990
Wildlife Dis Assoc |
Subjects | |
Online Access | Get full text |
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Summary: | Three attenuated rabies virus vaccines (SAD-B19, ERA/BHK-21, AZA 2) were compared for efficacy and safety in the striped skunk (Mephitis mephitis) by the oral and intranasal routes. The SAD-B19 and ERA/BHK-21 vaccines were given orally; all three vaccines were given intranasally. Oral administration of SAD-B19 and ERA/BHK-21 vaccines induced neither seroconversion nor significant protection against rabies challenge. One skunk which consumed a SAD-B19 vaccine-laden bait succumbed to vaccine-induced rabies. Intranasal instillation of the three vaccines resulted in the deaths of two of six (AZA 2), three of six (ERA/BHK-21) and six of six (SAD-B19) skunks. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0090-3558 1943-3700 |
DOI: | 10.7589/0090-3558-26.1.99 |