Risk of adverse events and reported clinical relapse after COVID-19 vaccination in patients with IBD

According to univariate and multivariate analyses (online supplemental file 1) and in line with a recent survey by Botwin et al,7 AEs are more common among younger patients (OR 0.96, p<0.0005) and in cases of previous COVID-19 infection (OR 2.3, p=0.021). Regarding ongoing therapy, we found azath...

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Bibliographic Details
Published inGut Vol. 71; no. 9; pp. 1926 - 1928
Main Authors Cannatelli, Rosanna, Ferretti, Francesca, Carmagnola, Stefania, Bergna, Irene Maria Bambina, Monico, Maria Camilla, Maconi, Giovanni, Ardizzone, Sandro
Format Journal Article
LanguageEnglish
Published London BMJ Publishing Group Ltd and British Society of Gastroenterology 01.09.2022
BMJ Publishing Group LTD
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Summary:According to univariate and multivariate analyses (online supplemental file 1) and in line with a recent survey by Botwin et al,7 AEs are more common among younger patients (OR 0.96, p<0.0005) and in cases of previous COVID-19 infection (OR 2.3, p=0.021). Regarding ongoing therapy, we found azathioprine (OR 0.39) to be inversely correlated to the presence of any AEs, while anti-tumour necrosis factor therapy (OR 2.01) was statistically significant only in the univariate analysis. [...]in the multivariate analysis, female gender was found to be a risk factor for developing any AEs (OR 1.96). [...]our data were based on a short-term follow-up and further studies on long-term AEs with objective markers are needed to state clearer recommendations.
Bibliography:Letter
SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0017-5749
1468-3288
DOI:10.1136/gutjnl-2021-326237