Equine multinodular pulmonary fibrosis in horses in the UK

Infection of MHV-68 in a natural host, the wood mouse (Apodemus sylvaticus), is associated with lower viral titres than in laboratory mice ( Hughes and others 2010 ). [...]the outcome of MHV-68 infection in laboratory mice should be interpreted with caution, when inferring parallels with other natur...

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Published inVeterinary record Vol. 169; no. 12; p. 313
Main Authors Soare, T., Leeming, G., Morgan, R., Papoula-Pereira, R., Kipar, A., Stewart, J. P., Hetzel, U.
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Limited 17.09.2011
Blackwell Publishing Ltd
Subjects
Animals
Colleges & universities
Deoxyribonucleic acid
DNA
Fatal Outcome
Herpesviridae Infections - pathology
Herpesviridae Infections - veterinary
Herpesviridae Infections - virology
Horse Diseases - pathology
Horse Diseases - virology
Horses
Infections
Laboratories
Lung - pathology
Lung - virology
Lungs
Male
Neutrophils
Pathogenesis
Pulmonary fibrosis
Pulmonary Fibrosis - pathology
Pulmonary Fibrosis - veterinary
Pulmonary Fibrosis - virology
Rodents
United Kingdom > UK
Europe
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Summary:Infection of MHV-68 in a natural host, the wood mouse (Apodemus sylvaticus), is associated with lower viral titres than in laboratory mice ( Hughes and others 2010 ). [...]the outcome of MHV-68 infection in laboratory mice should be interpreted with caution, when inferring parallels with other natural gammaherpesvirus infections. [...]investigation into the pathogenesis of pulmonary fibrosis and its potential association with gammaherpesviruses is required.
Bibliography:Dr Soare is also at the University of Agriculture Sciences and Veterinary Medicine Bucharest, Bucharest, Romania
ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ObjectType-Report-1
ObjectType-Article-3
ISSN:0042-4900
2042-7670
DOI:10.1136/vr.d4348