1 day of nitrofurantoin was not as effective as 7 days for asymptomatic bacteriuria in pregnancy

Aug 1, 2009 Guidelines from the Infectious Diseases Society of America suggest that asymptomatic bacteriuria (found in 1-2% of pregnancies) should be treated with a short course (3-7 d) of antimicrobial therapy. 1 This approach will clear asymptomatic bacteriuria and reduce low birth weight (a surro...

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Published inBMJ evidence-based medicine Vol. 14; no. 4; p. 113
Main Authors Vousden, Nicola, Shennan, Andrew H
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd 01.08.2009
BMJ Publishing Group LTD
Subjects
Age
Antibiotics
Birth weight
Compliance
Congenital diseases
Obstetrics
Pregnancy
Premature birth
Womens health
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Summary:Aug 1, 2009 Guidelines from the Infectious Diseases Society of America suggest that asymptomatic bacteriuria (found in 1-2% of pregnancies) should be treated with a short course (3-7 d) of antimicrobial therapy. 1 This approach will clear asymptomatic bacteriuria and reduce low birth weight (a surrogate for preterm delivery). The 1-day course was not associated with increased adverse perinatal outcomes; thus, it may be just as efficacious as a 7-day course for end points that matter. [...]for situations in which compliance and cost are problematic, a 1-day antibiotic treatment could be beneficial, although a 7-day course is preferable if feasible.
Bibliography:local:ebmed;14/4/113
href:ebmed-14-113.pdf
ArticleID:ebm9152
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ISSN:1356-5524
2515-446X
1473-6810
2515-4478
DOI:10.1136/ebm.14.4.113