Neurological manifestation of cholesterinic granulomas in three horses

Cholesterinic granulomas have been previously reported as an incidental post mortem in horses. Three adult horses with diencephalic dysfunction due to cholesterinic granulomas are described. All the horses exhibited profound depression, somnolence and reluctance to move. One horse experienced genera...

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Bibliographic Details
Published inVeterinary record Vol. 135; no. 10; p. 228
Main Authors Jackson, C A, deLahunta, A, Dykes, N L, Divers, T J
Format Journal Article
LanguageEnglish
Published England 03.09.1994
Subjects
Animals
Brain Diseases - complications
Brain Diseases - etiology
Brain Diseases - pathology
Brain Diseases - veterinary
Cholesterol
Female
Granuloma, Foreign-Body - complications
Granuloma, Foreign-Body - pathology
Granuloma, Foreign-Body - veterinary
Horse Diseases - etiology
Horse Diseases - pathology
Horses
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Summary:Cholesterinic granulomas have been previously reported as an incidental post mortem in horses. Three adult horses with diencephalic dysfunction due to cholesterinic granulomas are described. All the horses exhibited profound depression, somnolence and reluctance to move. One horse experienced generalised seizures. Cerebrosinal fluid was xanthochromic with an elevated total protein in two of the cases evaluated. The large cholesterinic granulomas caused expansion of the lateral ventricle and secondary hydrocephalus due to the build up of cerebrospinal fluid behind the mass. Cholesterinic granulomas are believed to result from choroid plexus congestion and haemorrhage.
ISSN:0042-4900
DOI:10.1136/vr.135.10.228