Disruption of Chrysomya megacephala Growth Caused by Lignan Grandisin

• Published in: Journal of medical entomology Vol. 46; no. 2; pp. 281 - 283
• Main Authors: Nogueira, Camila Diniz Ribeiro, Mello, Rubens Pinto de, Kato, Massuo Jorge, Cabral, Marise Maleck de Oliveira
• Format: Journal Article
• Language: English
• Published: England 01.03.2009
• Subjects: Animals; Chrysomya megacephala; dietary exposure; Diptera - drug effects; Diptera - growth & development; furans; Furans - isolation & purification; Furans - pharmacology; Insect Control; insect development; insect growth; insecticidal properties; Insecticides - isolation & purification; larvae; lignans; Lignans - isolation & purification; Lignans - pharmacology; Metamorphosis, Biological - drug effects; ova; Piper - chemistry; postembryonic development; topical application; toxicity; Toxicity Tests
• ISSN: 0022-2585; 1938-2928
• DOI: 10.1603/033.046.0212

The toxicity of tetrahydrofuran lignan grandisin was evaluated against larvae of Chry somya megacephala F. (Diptera: Calliphoridae). The bioassay involved topical treatment on larvae topical treatment on egg masses, and incorporation in the larval diet. Grandisin showed inhibition of postembryonic development by ovicidal (30%) and larvicidal (38%) effects and reduced larval weigh (4 mg), when topically applied on egg masses and starving larvae (L1) at a concentration of 100 μg/ μl. These findings elucidated the effect of grandisin on the C. megacephala life cycle and its potential to control C. megacephala populations.