Presumed disseminated carcinomatosis of the bone marrow in a dog

An eight-year-old male neutered Jack Russell terrier presented with fever, shoulder and elbow pain and progressive right forelimb lameness. Haematology revealed a non-regenerative anaemia and marked thrombocytopenia. Radiography and CT of the thorax and abdomen revealed bilateral asymmetrical osteog...

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Bibliographic Details
Published inVeterinary record case reports Vol. 8; no. 3
Main Authors Jardim Gomes, Bárbara Andreia, Gunn, Eilidh, Millins, Caroline, Waugh, Elspeth M, Hammond, Gawain
Format Journal Article
LanguageEnglish
Published London British Veterinary Association 01.09.2020
Blackwell Publishing Ltd
Subjects
Abdomen
Bone marrow
bone marrow carcinomatosis
bone metastasis
Case reports
Cytokeratin
dog
Histopathology
Hyperplasia
Metastasis
Pain
radiography
Thorax
Vertebrae
United Kingdom > UK
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Summary:An eight-year-old male neutered Jack Russell terrier presented with fever, shoulder and elbow pain and progressive right forelimb lameness. Haematology revealed a non-regenerative anaemia and marked thrombocytopenia. Radiography and CT of the thorax and abdomen revealed bilateral asymmetrical osteogenic-osteolytic changes to the scapulae, humeri, femurs, pelvis, ribs and vertebrae. Histopathology of the bone marrow of the left humerus confirmed a metastatic skeletal adenocarcinoma. This case features a presumptive manifestation of disseminated carcinomatosis of the bone marrow with a bilateral asymmetrical distribution in a metastatic adenocarcinoma of unknown primary origin. Disseminated carcinomatosis of the bone marrow should be included in the differential diagnosis with polyostotic osteolytic and osteogenic, bilateral asymmetrical lesions in the long bones, vertebrae, ribs and pelvis.
ISSN:2052-6121
2052-6121
DOI:10.1136/vetreccr-2019-000979