Different threshold for prolactin response to hypoglycaemia in patients with rheumatoid arthritis?

Using the same stress stimulus as in the study of Eijsbouts et al, 1 we showed that the PRL response to hypoglycaemia was decreased in 38 patients with long term RA with moderate disease activity who were receiving treatment with NSAIDs or DMARDs. 3 In line with others, 4, 5 we observed a PRL respon...

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Bibliographic Details
Published inAnnals of the rheumatic diseases Vol. 64; no. 3; pp. 515 - 516
Main Authors Imrich, R, Vigas, M, Rovensky, J
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd and European League Against Rheumatism 01.03.2005
Elsevier Limited
Subjects
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Antirheumatic Agents - therapeutic use
Arthritis, Rheumatoid - blood
Disease
Growth hormones
Humans
hypoglycaemia
Hypoglycemia - blood
Matters Arising
Pituitary gland
prolactin
Prolactin - blood
Rheumatism
Rheumatoid arthritis
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Summary:Using the same stress stimulus as in the study of Eijsbouts et al, 1 we showed that the PRL response to hypoglycaemia was decreased in 38 patients with long term RA with moderate disease activity who were receiving treatment with NSAIDs or DMARDs. 3 In line with others, 4, 5 we observed a PRL response to thyrotropin releasing hormone stimulation comparable to the response in healthy subjects in the same cohort of patients, 3 suggesting a normal pituitary gland but altered central neuroendocrine regulatory mechanisms in patients with moderately active RA.
Bibliography:local:0640515
href:annrheumdis-64-515.pdf
PMID:15708916
istex:CCECEF208FA4395D4084581801E17506A7A39D15
ark:/67375/NVC-WKRBL418-C
Correspondence to:
 Dr R Imrich
 Institute of Experimental Endocrinology, Slovak Academy of Sciences, Vlarska 3, 833 06 Bratislava, Slovakia; richard.imrich@savba.sk
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ISSN:0003-4967
1468-2060