Anatomy and biochemistry of entheses

Dec 1, 2000 Volume: 59 Background-Treatment with anti-tumour necrosis factor α (anti-TNFα) monoclonal antibodies has been successfully applied to patients with rheumatoid arthritis. Because TNFα has been detected in inflamed sacroiliac joints in patients with AS we investigated the efficacy of th...

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Bibliographic Details
Published inAnnals of the rheumatic diseases Vol. 59; no. 12; pp. 995 - 999
Main Author BENJAMIN, MICHAEL
Format Journal Article
LanguageEnglish
Published London BMJ Publishing Group Ltd and European League Against Rheumatism 01.12.2000
BMJ Publishing Group Ltd
BMJ Publishing Group LTD
Subjects
Abstracts
Antigens
Biochemistry
Bone marrow
Calcification
Collagen
Cytokines
Inflammation
Ligaments
Lymphocytes
NMR
Nuclear magnetic resonance
Physiological aspects
Proteins
Stress concentration
Tendons
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Summary:Dec 1, 2000 Volume: 59 Background-Treatment with anti-tumour necrosis factor α (anti-TNFα) monoclonal antibodies has been successfully applied to patients with rheumatoid arthritis. Because TNFα has been detected in inflamed sacroiliac joints in patients with AS we investigated the efficacy of this treatment also in these patients. Because SpA is strongly associated with HLA-B27 and gut or uninogenital pathology, immunity to an insult agent in gut or uninogenital tract may break the immune tolerance to PG or G1 in an SpA susceptible (HLA-B27) population by molecular mimicry mechanisms.
Bibliography:local:annrheumdis;59/12/995
href:annrheumdis-59-995.pdf
ark:/67375/NVC-N7G8LP44-4
istex:70E3901848D570BB8D8FBFCC1B8C99F3212C09F8
ISSN:0003-4967
1468-2060
DOI:10.1136/ard.59.12.995