CMR assessment of myocardial mechanics and tissue characterization in patients treated with Anthracycline chemotherapy for acute myeloid leukaemia

The period between Anthracycline therapy and onset of overt heart failure is often years, even decades, and as such Anthracyclines appear to initiate a myocardial injury that remains clinically silent for a substantial period of time. Conclusions In this small group of patients who received chemothe...

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Published inJournal of cardiovascular magnetic resonance Vol. 14; no. S1; p. P182
Main Authors Miller, Christopher A, Potluri, Rahul, Schmitt, Matthias
Format Journal Article
LanguageEnglish
Published New York BioMed Central 01.02.2012
BioMed Central Ltd
Elsevier
Subjects
Cardiology
Chemotherapy
Heart attacks
Medical research
Poster Presentation
Scholarships & fellowships
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Summary:The period between Anthracycline therapy and onset of overt heart failure is often years, even decades, and as such Anthracyclines appear to initiate a myocardial injury that remains clinically silent for a substantial period of time. Conclusions In this small group of patients who received chemotherapy for AML a mean of 7 years previously, there was no association between cumulative Anthracycline dose and peak systolic circumferential strain or a marker of diffuse myocardial fibrosis.
ISSN:1532-429X
1097-6647
1532-429X
DOI:10.1186/1532-429X-14-S1-P182