C-terminal part of alpha-synuclein mediates its activity in promoting proliferation of dopaminergic cells

α-Syn has been shown to exhibit a MAP-like activity and promote the assembly of microtubules. Since microtubules play a pivotal role in proliferative cell division, it is possible that α-syn affects cell proliferation by facilitating microtubule assembly.

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Bibliographic Details
Published inMolecular neurodegeneration Vol. 7; no. S1; p. S21
Main Authors Yin, Juanjuan, Wang, Tao, Han, Junyan, Zhang, Chen, Ma, Qiulan, Li, Xin, Cheng, Furong, Liu, Guangwei, Li, Yaohua, Uéda, Kenji, Chan, Piu, Yu, Shun
Format Journal Article
LanguageEnglish
Published London BioMed Central 07.02.2012
BioMed Central Ltd
BMC
Subjects
Hospitals
Meeting Abstract
Neurodegeneration
Neurosciences
Proteins
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Summary:α-Syn has been shown to exhibit a MAP-like activity and promote the assembly of microtubules. Since microtubules play a pivotal role in proliferative cell division, it is possible that α-syn affects cell proliferation by facilitating microtubule assembly.
ISSN:1750-1326
1750-1326
DOI:10.1186/1750-1326-7-S1-S21