Puromycin-sensitive aminopeptidase is involved in wild-type huntingtin clearance

From: 2011 International Conference on Molecular Neurodegeneration Shanghai, China 22-24 September 2011 Author details1-Division of Neuroscience, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USAEMPTY2-Department of Biochemistry and Molecular Biology, M...

Full description

Saved in:
Bibliographic Details
Published inMolecular neurodegeneration Vol. 7; no. S1; p. S5
Main Authors Ren, Guijie, Ma, Zonghcai, Hui, Maria, Kudo, Lili C, Hui, Koon-Sea, Karsten, Stanislav L
Format Journal Article
LanguageEnglish
Published London BioMed Central 07.02.2012
BioMed Central Ltd
BMC
Subjects
Artificial chromosomes
Biomedical research
Meeting Abstract
Neurodegeneration
Neurotoxicity
Pathogenesis
Rodents
Online AccessGet full text

Cover

More Information
Summary:From: 2011 International Conference on Molecular Neurodegeneration Shanghai, China 22-24 September 2011 Author details1-Division of Neuroscience, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USAEMPTY2-Department of Biochemistry and Molecular Biology, Medical College, Shandong University, Jinan, Shandong, 250012, ChinaEMPTY3-Nathan S. Kline Institute for Psychiatric Research, New York University School of Medicine, Orangeburg, NY 10962, USAEMPTY4-NeuroInDx Inc., 1655 East 28th Street, Signal Hill, CA 90755, USAEMPTY5-Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USAEMPTY Supplemental Information: Methods We first determined whether PSA regulates Htt abundance in vivo using a human PSA (hPSA) transgenic mouse model, which was generated using bacterial artificial chromosome (BAC) mediated technology.
ISSN:1750-1326
1750-1326
DOI:10.1186/1750-1326-7-S1-S5