P1-105 Incidence of severe acute respiratory infections (SARI) and deaths associated with influenza
BackgroundRespiratory infections are one of the leading causes of morbidity and mortality worldwide: influenza is one of the predominant pathogens responsible. During 2010, Paraguay actively sought for pH1N1 case-patients to estimate the incidence of severe acute respiratory infections (SARI) and de...
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Published in | Journal of epidemiology and community health (1979) Vol. 65; no. Suppl 1; p. A96 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
London
BMJ Publishing Group Ltd
01.08.2011
BMJ Publishing Group LTD |
Online Access | Get full text |
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Summary: | BackgroundRespiratory infections are one of the leading causes of morbidity and mortality worldwide: influenza is one of the predominant pathogens responsible. During 2010, Paraguay actively sought for pH1N1 case-patients to estimate the incidence of severe acute respiratory infections (SARI) and deaths associated with influenza.ObjectiveTo determine the contribution of Influenza in patients hospitalised with clinical evidence of severe acute respiratory infections (SARI).MethodsDuring 1 January 2010–31 December 2010, hospital staff identified all case-patients who met the SARI definition of sudden onset fever, and cough or sore throat, with shortness of breath requiring hospitalisation. Physicians obtained nasal and pharyngeal swabs from case-patients and sent the samples to the Paraguay National Influenza Center for influenza testing by immunofluorescence and reverse transcriptase polymerase chain reaction.ResultsHospital staff identified 2145 SARI cases of which they tested 1581 (74%) for influenza. Of these 284 cases (18%) were positive for influenza. The most frequently subtypes identified viruses were Influenza A H3N2 71% (202/284), influenza A H1N1 14% (41/284), influenza B 14% (41/ 284). We estimated that the rate of influenza-associated mortality was 2.8/100 000 persons-year (py).ConclusionOut findings suggest that influenza caused a significant burden and may warrant further investments in its control and prevention. |
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Bibliography: | istex:03A48AB9EB21BF90EE6B146DEFD3ED79FAD3AD30 local:jech;65/Suppl_1/A96-a ark:/67375/NVC-XFK300GV-R href:jech-65-A96-1.pdf ArticleID:jech142976c.98 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 0143-005X 1470-2738 |
DOI: | 10.1136/jech.2011.142976c.98 |