GI highlights from the literature

• Published in: Gut Vol. 63; no. 9; pp. 1522 - 1523
• Main Author: McLean, Mairi H
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 01.09.2014
• Subjects: Gastroenterology; Hepatology; Liver cirrhosis; Liver diseases; Mutation; Obesity; Rodents; Stem cells

By contrast, SFB depletion led to reduced IL-17A and lessened liver damage. [...]obesity-induced alterations to the gut microbiome may play a critical role in the up-regulation of cytokines, such as IL-17A leading to enhanced hepatic inflammation and NAFLD progression. [...]a higher proportion of th...