Derivatization in Analytical Chemistry

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: 2-naphthalenethiol; 96-microwell spectrophotometric assay; A/P ratio; acetazolamide; acetonitrile-related adducts; acetylenic lipids; amino acids; Analytical chemistry; biogenic amines; blood plasma; BSTFA; carbonic anhydrase; charge-transfer reaction; chemical warfare agents; Chemistry; chiral metabolomics; chloranilic acid; clams; creatine; creatinine; d-amino acids; derivatisation; derivatization; dimethyl labeling; double and triple bond localization; enantiomer separation; enhancement; esterification; fluorescence detection; fluorosurfactant-modified gold nanoparticles; GC-MS; glutamine; high-performance liquid chromatography; high-resolution mass spectrometry; high-throughput pharmaceutical analysis; homocysteine; homocysteine thiolactone; HPLC; HPLC-UV/Vis; human serum albumin; in-source derivatization; inhibition; linseed oil; low-molecular-weight thiols; Lycium barbarum L; mass spectrometry; Mathematics and Science; methylation; monobromobimane; nerve agents; Novichoks; o-phthalaldehyde; P/S ratio; pentafluorobenzyl bromide; pentafluoropropionic anhydride; pharmacokinetics; pigment; quantification; reduction; Reference, Information and Interdisciplinary subjects; Research and information: general; rice water; sarin; silylation; sodium borohydride; stability; sulforaphane; taurine; TMS; toluene; tyrosine kinase inhibitors; ureide; validation; zone fluidics; α-lipoic acid
• ISBN: 9783036542560; 3036542558; 9783036542553; 3036542566
• DOI: 10.3390/books978-3-0365-4255-3

Derivatization is one of the most widely used sample pretreatment techniques in Analytical Chemistry and Chemical Analysis. Reagent-based or reagent-less schemes offer improved detectability of target compounds, modification of the chromatographic properties and/or the stabilization of sensitive compounds until analysis. Either coupled with separation techniques or as a “stand alone” analytical procedure, derivatization offers endless possibilities in all aspects of analytical applications.