398 Biopsy and surgical specimen anatomopathological concordance of aspiration, curettage and hysteroscopy in endometrial cancer patients

• Published in: International journal of gynecological cancer Vol. 29; no. Suppl 3; pp. A165 - A166
• Main Authors: Anton, C, Mayerhoff, E, Kleine, RT, Carvalho, JP
• Format: Journal Article
• Language: English
• Published: Oxford by the International Gynecologic Cancer Society and the European Society of Gynaecological Oncology 01.09.2019; BMJ Publishing Group LTD
• Subjects: Biopsy; Endometrial cancer; Medical diagnosis
• ISSN: 1048-891X; 1525-1438
• DOI: 10.1136/ijgc-2019-IGCS.398

ObjectivesTo explore the anatomopathological concordance of different diagnosis methods in endometrial cancer.MethodsA retrospective analysis of 824 patients with endometrial cancer diagnosis referred to surgical treatment in Instituto do Câncer do Estado de São Paulo between January 2009 and February 2019 was performed. Data has been exported from the REDCap database. The proportions of concordance of the exact anatomopathological results (histological type and grade) and the histological grade alone (high or low grade) between the diagnostic biopsy and the surgical specimen were calculated and compared for the following methods: endometrial aspiration, curettage and hysteroscopy (diagnose and operative).ResultsFrom the 824 analyzed patients, 628 had histological results from both a diagnostic biopsy and the surgical specimen. The diagnosis methods analyzed were: endometrial aspiration, curettage and hysteroscopy. The proportion of anatomopathological concordance between biopsy and surgical specimen can be seen in table 1. The exact concordance taking into account the histological type and grade was analyzed and in a second analysis the histological grade alone was evaluated. table 2 shows the comparison of the different methods.Abstract 398 Table 1Hystological concordance between biopsy and final specimen in different diagonsisAbstract 398 Table 2Proportion concordance diagnose comparison between different diagnosis methodsConclusionsEndometrial cancer diagnosis through endometrial aspiration or curettage had a better correlation of the histological grade with the surgical specimen when compared to hysteroscopy. In addition, endometrial aspiration is a cheaper and more accessible method than hysteroscopy and should therefore be stimulated as a diagnostic method for endometrial cancer.