Morphological spectrum of gallstone disease in 1100 cholecystectomies in North India
BACKGROUND: Gallstones are a major cause of morbidity and mortality throughout the world. In India, they are seven times more common in the North as compared to the South. AIMS: To study the morphological spectrum of gallstone disease in the stone- belt of India, and to understand its probable etiop...
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Published in | Indian journal of surgery Vol. 67; no. 3; p. 140 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
India
Medknow Publications on behalf of Association of Surgeons of India
01.05.2005
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Summary: | BACKGROUND: Gallstones are a major cause of morbidity and mortality
throughout the world. In India, they are seven times more common in the
North as compared to the South. AIMS: To study the morphological
spectrum of gallstone disease in the stone- belt of India, and to
understand its probable etiopathogenesis. MATERIALS AND METHODS:
Morphological spectrum of gallstone disease was studied in 1100
cholecystectomies over a period of 3 years in the past. RESULTS: There
was a preponderance of females (M: F ratio 1: 6.4). The age of the
patients varied from 10 to 90 years with maximum number of cases
between 31 and 40 years of age. On morphological analysis, gallstones
were of mixed type in 686 cases (62.3%), pigment type in 34 cases
(3.2%), cholesterol type in 182 cases (17.3%), and combined type in 148
cases (14%). Other lesions associated with chronic cholecystitis were
cholesterolosis in 112 cases (10.1%), xanthogranulomatous cholecystitis
in 26 cases (2.3%), follicular cholecystitis in 26 cases (2.3%), ceroid
granulomas in ten cases (0.9%), eosinophilic cholecystitis in six cases
(0.5%), and carcinoma in 12 cases (1.09%). Maximum number of carcinomas
were associated with pigment stones, that is, 7 out of 12 cases
(58.3%). CONCLUSIONS: The morphological spectrum of gallstone disease
in this stone-belt of India will certainly contribute to understand its
etiopathogenesis, and hence prevention. However, further studies on the
biochemical composition of stones and their association with
morphological changes are required to clarify the etiopathogenesis. |
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ISSN: | 0972-2068 0973-9793 |