Cerebral Xanthoma in a Peron's Tree Frog (Litoria peronii)

An 11-yr-old Peron's tree frog (Litoria peronii) was presented with neurologic signs progressing from head bobbing to circling and incoordination. Postmortem and histologic evaluations demonstrated the presence of a cerebral xanthoma, a large cholesterol granuloma expanding the leptomeninges. T...

Full description

Saved in:
Bibliographic Details
Published inJournal of herpetological medicine and surgery Vol. 25; no. 1-2; pp. 21 - 23
Main Authors Hill, Andrew Gordon, Mackie, John Thomas
Format Journal Article
LanguageEnglish
Published Association of Reptilian and Amphibian Veterinarians 01.03.2015
Subjects
Online AccessGet full text

Cover

Loading…
Abstract An 11-yr-old Peron's tree frog (Litoria peronii) was presented with neurologic signs progressing from head bobbing to circling and incoordination. Postmortem and histologic evaluations demonstrated the presence of a cerebral xanthoma, a large cholesterol granuloma expanding the leptomeninges. The nodule in the cerebral cortex consisted of arrays of cholesterol clefts surrounded by foamy vacuolated macrophages. The factors leading to focal cerebral xanthomatosis are unclear, and the relationship between trauma, dietary lipid composition, hypercholesterolemia, and xanthomas in amphibians requires further investigation.
AbstractList An 11-yr-old Peron's tree frog (Litoria peronii) was presented with neurologic signs progressing from head bobbing to circling and incoordination. Postmortem and histologic evaluations demonstrated the presence of a cerebral xanthoma, a large cholesterol granuloma expanding the leptomeninges. The nodule in the cerebral cortex consisted of arrays of cholesterol clefts surrounded by foamy vacuolated macrophages. The factors leading to focal cerebral xanthomatosis are unclear, and the relationship between trauma, dietary lipid composition, hypercholesterolemia, and xanthomas in amphibians requires further investigation.
Author Mackie, John Thomas
Hill, Andrew Gordon
Author_xml – sequence: 1
  givenname: Andrew Gordon
  surname: Hill
  fullname: Hill, Andrew Gordon
  organization: 1. Currumbin Wildlife Sanctuary Hospital, 28 Tomewin Street, Currumbin, Queensland, Australia, 4223
– sequence: 2
  givenname: John Thomas
  surname: Mackie
  fullname: Mackie, John Thomas
  organization: 2. Veterinary Pathology, Vepalabs, 26 Balaclava Street, Woolloongabba, Queensland, 4102
BookMark eNqNkLFOwzAQhi1UJErpA7B5A4akPtuXxGwoagEpEgxFYrPsxAGjNq7sLrw9iYqYueFu-PWd9P2XZDaEwRFyDSzHCqoVIFeZKhAyjjnkHM7InItSZgqZnJH5X35Blil9sXFQFlLIObmvXXQ2mh19N8PxM-wN9QM19NXFMNwkuo3O0U0MH_S28ccQvaGHKfL-7oqc92aX3PL3LsjbZr2tn7Lm5fG5fmgyC4JBpjhXVQdClZ3lHbOFaB0ypUzLOuRWmraAFg1WvSxbiWD7rpMVB5TSKqaYWBA4_W1jSCm6Xh-i35v4rYHpyV9Pfnry0xz1uGBkVifG-jB29Q_iB-NnWyI
CitedBy_id crossref_primary_10_1053_j_jepm_2020_01_002
Cites_doi 10.1136/vr.158.18.636
10.1136/vr.135.10.228
10.1638/2009-0175.1
10.1177/030098588602300320
ContentType Journal Article
Copyright 2015 Association of Reptilian and Amphibian Veterinarians
Copyright_xml – notice: 2015 Association of Reptilian and Amphibian Veterinarians
DBID AAYXX
CITATION
DOI 10.5818/1529-9651-25.1.21
DatabaseName CrossRef
DatabaseTitle CrossRef
DatabaseTitleList
DeliveryMethod fulltext_linktorsrc
Discipline Veterinary Medicine
EISSN 2374-9504
EndPage 23
ExternalDocumentID 10_5818_1529_9651_25_1_21
GroupedDBID 5GY
AACFU
AAPSS
ABDBF
ABPTK
AEDJY
AKPMI
ALMA_UNASSIGNED_HOLDINGS
EBD
EBS
EJD
ESX
PQ0
TUS
VH1
Y3D
AAHBH
AAYXX
AFFIJ
AFNWH
CITATION
EYRJQ
ID FETCH-LOGICAL-b1301-92298d1397db2d0b63ce5099ac0d52b4ac61c5a58f47c451bfdd4821544b90903
ISSN 1529-9651
IngestDate Fri Aug 23 02:43:53 EDT 2024
Thu Nov 04 13:51:07 EDT 2021
IsPeerReviewed true
IsScholarly true
Issue 1-2
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-b1301-92298d1397db2d0b63ce5099ac0d52b4ac61c5a58f47c451bfdd4821544b90903
PageCount 3
ParticipantIDs crossref_primary_10_5818_1529_9651_25_1_21
bioone_primary_10_5818_1529_9651_25_1_21
PublicationCentury 2000
PublicationDate 20150300
2015-3-1
PublicationDateYYYYMMDD 2015-03-01
PublicationDate_xml – month: 3
  year: 2015
  text: 20150300
PublicationDecade 2010
PublicationTitle Journal of herpetological medicine and surgery
PublicationYear 2015
Publisher Association of Reptilian and Amphibian Veterinarians
Publisher_xml – name: Association of Reptilian and Amphibian Veterinarians
References Russell WC (i1529-9651-25-1-21-b12) 1990; 21
i1529-9651-25-1-21-b10
Garner MM (i1529-9651-25-1-21-b4) 1999; 30
i1529-9651-25-1-21-b1
i1529-9651-25-1-21-b2
Carpenter JL (i1529-9651-25-1-21-b3) 1986; 23
i1529-9651-25-1-21-b8
References_xml – ident: i1529-9651-25-1-21-b1
  doi: 10.1136/vr.158.18.636
– ident: i1529-9651-25-1-21-b8
  doi: 10.1136/vr.135.10.228
– volume: 21
  start-page: 99
  year: 1990
  ident: i1529-9651-25-1-21-b12
  publication-title: J Zoo Wildl Med
  contributor:
    fullname: Russell WC
– ident: i1529-9651-25-1-21-b10
  doi: 10.1638/2009-0175.1
– volume: 30
  start-page: 443
  year: 1999
  ident: i1529-9651-25-1-21-b4
  publication-title: J Zoo Wildl Med
  contributor:
    fullname: Garner MM
– ident: i1529-9651-25-1-21-b2
– volume: 23
  start-page: 337
  year: 1986
  ident: i1529-9651-25-1-21-b3
  publication-title: Vet Pathol
  doi: 10.1177/030098588602300320
  contributor:
    fullname: Carpenter JL
SSID ssj0000546434
Score 1.9479352
Snippet An 11-yr-old Peron's tree frog (Litoria peronii) was presented with neurologic signs progressing from head bobbing to circling and incoordination. Postmortem...
SourceID crossref
bioone
SourceType Aggregation Database
Publisher
StartPage 21
SubjectTerms Amphibian
CASE REPORTS
cholesterol
granuloma
Litoria peronii
xanthomatosis
Title Cerebral Xanthoma in a Peron's Tree Frog (Litoria peronii)
URI http://www.bioone.org/doi/abs/10.5818/1529-9651-25.1.21
Volume 25
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Pb9MwFLbQduGCYIAYA-QD0gZVSuLEbcKtGxsTopw61FtkO44UwVLUlgP89XwvtpuIITG4WKnVOOp7X14_v19m7GUudApaW0fTqk7JdaMjXccy0oWKbaVTcFgqTp5_mlxeZR-Wctmn8nbVJVs9Nj__WFfyP1rFHPRKVbL_oNndopjANfSLERrGeCsdn9k1xX2_jpaKegBcK_JeKMpqX7mTUhZra8FNV5034GNDDUEUdSrGi9wEH8BNZgo1gkvvrGIIv3dxhs2gjLrzWLuwhcuLHL3HVraP68-V-dLYkPA7zEXyboZE9nlWDhg9WFyXFBi0zg9Dj54BeFTg0o4-Uw4PFRLjw2ZoVgX1AfWtZW03J9JpFhXSHT4cbLErgg6Y84WRwbQO_qRdjfLv5l-CfZAnIjwtEnKcjKnNwL6YFhJ78_3Z6bvTi50TDnwVjKzLPAj3uMg3rfTmxjpgKbpZrVo7IDEDNrK4z-55ZfGZw8QDdse2B-xgJ5cffO6V9pC9DSjhASW8abniHUqON5wwwgkj_MQjhHuEvHrEri7OF2eXkT8xI9LgIklUCFHkFZH6Sosq1pPUWDDCQpm4kkJnykwSI5XM62xqMpnouqqyXFBHJl2Qx-4x22vx-54wjjtVqlUda4VNtLJ5AepsYN-NyrNMTQ7ZiZNF-c21RSmxnSSxlSS2ksRWClliSA7Z6yCtv3_56e3XPWJ3e6Q-Y3vb9Xf7HBRxq194Rf8CPA1g-Q
link.rule.ids 315,786,790,27957,27958
linkProvider EBSCOhost
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cerebral+Xanthoma+in+a+Peron%27s+Tree+Frog+%28Litoria+peronii%29&rft.jtitle=Journal+of+herpetological+medicine+and+surgery&rft.au=Hill%2C+Andrew+Gordon&rft.au=Mackie%2C+John+Thomas&rft.date=2015-03-01&rft.pub=Association+of+Reptilian+and+Amphibian+Veterinarians&rft.issn=1529-9651&rft.eissn=2374-9504&rft.volume=25&rft.issue=1-2&rft.spage=21&rft.epage=23&rft_id=info:doi/10.5818%2F1529-9651-25.1.21
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1529-9651&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1529-9651&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1529-9651&client=summon