Cerebral Xanthoma in a Peron's Tree Frog (Litoria peronii)

An 11-yr-old Peron's tree frog (Litoria peronii) was presented with neurologic signs progressing from head bobbing to circling and incoordination. Postmortem and histologic evaluations demonstrated the presence of a cerebral xanthoma, a large cholesterol granuloma expanding the leptomeninges. T...

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Published inJournal of herpetological medicine and surgery Vol. 25; no. 1-2; pp. 21 - 23
Main Authors Hill, Andrew Gordon, Mackie, John Thomas
Format Journal Article
LanguageEnglish
Published Association of Reptilian and Amphibian Veterinarians 01.03.2015
Subjects
Amphibian
CASE REPORTS
cholesterol
granuloma
Litoria peronii
xanthomatosis
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Summary:An 11-yr-old Peron's tree frog (Litoria peronii) was presented with neurologic signs progressing from head bobbing to circling and incoordination. Postmortem and histologic evaluations demonstrated the presence of a cerebral xanthoma, a large cholesterol granuloma expanding the leptomeninges. The nodule in the cerebral cortex consisted of arrays of cholesterol clefts surrounded by foamy vacuolated macrophages. The factors leading to focal cerebral xanthomatosis are unclear, and the relationship between trauma, dietary lipid composition, hypercholesterolemia, and xanthomas in amphibians requires further investigation.
ISSN:1529-9651
2374-9504
DOI:10.5818/1529-9651-25.1.21