4CPS-394 Evaluation of the degree of therapeutic knowledge in lung transplant recipients

• Published in: European journal of hospital pharmacy. Science and practice Vol. 28; no. Suppl 1; p. A110
• Main Authors: Sanabrias Fernandez De Sevilla, R, Calvo Salvador, M, Gumiel Baena, I, García Cerezuela, MD, Lozano Llano, C, Repilado Álvarez, A, Sanz Rodríaguez, SM, Alcaraz López, JI, Muñoz Gómez, T, Ussetti Gil, MP, Sánchez Guerrero, A
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 01.03.2021
• Subjects: Conflicts of interest; Lung transplants
• ISSN: 2047-9956; 2047-9964
• DOI: 10.1136/ejhpharm-2021-eahpconf.226

Background and importanceLung transplant (LT) recipients require intensive and continuous care due to the complexity and relevance of pharmacological treatments in the clinical course after transplantation. Acute rejection, infections and side effects of immunosuppressants are common, especially during the first year after transplantation. Patients must acquire knowledge and skills that allow them to actively participate in the control of their ‘new disease’.Aim and objectivesTo analyse the degree of LT recipient knowledge about their treatment in the immediate post-transplant period and to identify weaknesses and characteristics of the patients.Material and methodsA prospective observational study was conducted from June to December 2019, corresponding to the pilot phase of an e-learning programme in LT recipients (e-duca). We designed a 25 multiple answer question test which was completed by the patients before post-transplant discharge. Variables studied were: age, gender, LT indication, educational level, number of drugs prescribed at discharge, test score (TS) and answers correctly with more or less frequency. We considered a high degree of knowledge as a TS ≥20, moderate 13–20 and deficient <13.Results16 patients were included with a mean age of 61.4 years (48–68) and 81.3% (13) were men. The LT indication was COPD in 56.3% (9), idiopathic pulmonary fibrosis in 37.5% (6) and bronchiectasis in 6.2% (1). Educational levels were university (3), secondary (4) and basic (9). The average number of drugs prescribed at discharge was 14.31 (9–20). Mean TS was 14.56 (6–22), equivalent to 58.2% of correct answers. 31.3% (5) of patients demonstrated a poor degree of knowledge, 62.5% (10) moderate and 6.2% (1) high. The most frequently correct answers were related to how to take tacrolimus and mycophenolate (87.5%) and the function and duration of immunosuppressive treatment (93.8%). On the other hand, the least frequently correct answers were related to the role of adjuvant therapy: only to prevent infections (93.8%), to identify prednisone as immunosuppressant (56.3%) and acting correctly when vomiting after taking immunosuppressants (56.3%).Conclusion and relevanceThis type of test allows us to know the patients’ skills about their treatment and to identify which points need to be reinforced by the pharmacist as part of the healthcare team that attends to the patient. It also allows early detection of possible medication errors.References and/or acknowledgementsConflict of interestNo conflict of interest