IDDF2021-ABS-0211 Co-occurrence of gut microbiota dysbiosis and bile acid metabolism alteration is associated with psychological disorders in crohn’s disease

• Published in: Gut Vol. 70; no. Suppl 2; pp. A144 - A145
• Main Authors: Gao, Xuefeng, Feng, Lijuan, Zhou, Nan, Li, Zichun, Fu, Dongni, Guo, Ying, Liu, Xiaowei
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 01.09.2021
• Subjects: Acids; Bile; Bile acids; Biodiversity; Central nervous system; Crohn's disease; Deoxycholic acid; Dysbacteriosis; Enterobacteriaceae; Fecal microflora; Feces; Intestinal microflora; Liquid chromatography; Mass spectroscopy; Metabolism; Metabolites; Microbiota; Mucosa; rRNA 16S; Taurodeoxycholic acid

BackgroundMetabolites of the gut microbiota interviewing with signals derived from the host immune, endocrine, and neuronal systems intertwining may influence the development of mucosal injury and inflammation and impacts also distal central nervous system, underlying the psychophysiological vulnera...