2022-RA-752-ESGO The efficacy of HPV test for cervical cancer screening

• Published in: International journal of gynecological cancer Vol. 32; no. Suppl 2; p. A72
• Main Authors: Song, Heekyoung, Hong, Jiyun, Hur, Soo Young
• Format: Journal Article
• Language: English
• Published: Oxford BMJ Publishing Group Ltd 20.10.2022; BMJ Publishing Group LTD
• Subjects: Biopsy; Cellular biology; Cervical cancer; Cohort analysis; Diagnostics; Genetic testing; Human papillomavirus; Medical screening
• ISSN: 1048-891X; 1525-1438
• DOI: 10.1136/ijgc-2022-ESGO.158

Introduction/BackgroundAbout 3,218 new cervical cancer cases are diagnosed annually (estimations for 2020) and the third most common female cancer in women aged 15 to 44 years in Korea. For more than a half century, cervical cytology testing has been the foundation for screening for cervical cancer and the burden of this disease. Cervical cancer is now recognized to be caused by persistent infection of HPV which develop primarily as precancerous lesions and then progress to invasive cancer.MethodologyThe patients were selected in Korean HPV Cohort study and followed-up at every 6-month intervals. Only patients who had been tissue biopsy were included this study. We evaluated the results of cytology, HPV DNA test, and pathologic result of the included patients were compared with each other to check up efficacy of diagnosis between cytology and HPV DNA testing. This abstract was preliminary result.ResultsThe patients were selected in Korean HPV Cohort study and followed-up at every 6-month intervals. Only patients who had been tissue biopsy were included this study. We evaluated the results of cytology, HPV DNA test, and pathologic result of the included patients were compared with each other to check up efficacy of diagnosis between cytology and HPV DNA testing. This abstract was preliminary result.ConclusionThe use of HPV testing improved sensitivity better than liquid-based cytology with or without colposcopy-based biopsy. It recommends an HPV DNA based test as the preferred method, rather than cytology, currently the most commonly used methods to detect pre-cancer lesions.