Novel approaches to male hormonal contraception
The principal of male hormonal contraception has been investigated for the past 20 years. This thesis reviews what is known already from the literature and presents the results of three new clinical trials investigating different aspects of this approach. These trials were undertaken by myself as a...
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| Format | Dissertation |
| Language | English |
| Published |
University of Edinburgh
2008
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| Online Access | Get full text |
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| Summary: | The principal of male hormonal contraception has been investigated for the past 20 years. This thesis reviews what is known already from the literature and presents the results of three new clinical trials investigating different aspects of this approach. These trials were undertaken by myself as a member of the Contraceptive Development Network research groups at the University of Edinburgh. 1. A randomised single centre study comparing the effects of MENT Ac implants or testosterone pellets in combination with etonogestrel implants on spermatogenesis and androgen dependent tissues. 2. Investigation of the effects of gonadotrophin withdrawal and progesterone on hormone production, metabolism and action in the human testis- a randomised, controlled trial. 3. A single centre study comparing the 24 hour testosterone concentration in two groups of men: men receiving a hormonal contraceptive regime and a control group. |
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