The Occurrence or Fibrillary Glomerulonephritis in Patients with Diabetes Mellitus May Not Be Coincidental: A Report of Four Cases

Although clinical presentation of fibrillary glomerulonephritis is similar to most forms of glomerulonephritis, it is usually difficult to make the diagnosis. Clinical manifestations include proteinuria, microscopic haematuria, nephrotic syndrome, and impairment of renal function. A diagnosis of fib...

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Published inCase Reports in Medicine Vol. 2013; no. 2013; pp. 166 - 170-243
Main Authors Fayna González-Cabrera, Fernando Henríquez-Palop, Ana Ramírez-Puga, Raquel Santana-Estupiñán, Celia Plaza-Toledano, Gloria Antón-Pérez, Silvia Marrero-Robayna, Davinia Ramírez-Medina, Roberto Gallego-Samper, Nicanor Vega-Díaz, Rafael Camacho-Galan, José C. Rodríguez-Pérez
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Limiteds 01.01.2013
Hindawi Puplishing Corporation
Hindawi Publishing Corporation
Hindawi Limited
Wiley
Subjects
Biopsy
Care and treatment
Case Report
Case studies
Diabetes
Diagnosis
Disease
Edema
Glomerulonephritis
Hypertension
Light
Microscopy
Nephrology
Proteins
Risk factors
Type 2 diabetes
Urine
Spain
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Summary:Although clinical presentation of fibrillary glomerulonephritis is similar to most forms of glomerulonephritis, it is usually difficult to make the diagnosis. Clinical manifestations include proteinuria, microscopic haematuria, nephrotic syndrome, and impairment of renal function. A diagnosis of fibrillary glomerulonephritis is only confirmed by renal biopsy and it must comprise electronmicroscopy-verified ultrastructural findings. We report four cases between 45–50 years old with documented type 2 diabetes mellitus (T2DM) and arterial hypertension. All patients were found to have fibrils on kidney biopsy. The differential diagnosis of fibrils in the setting of diabetes mellitus is also discussed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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Academic Editor: Christian Koch
ISSN:1687-9627
1687-9635
DOI:10.1155/2013/935172