Batzelladines F−I, Novel Alkaloids from the Sponge Batzella sp.:  Inducers of p56lck-CD4 Dissociation

The sponge Batzella sp. from Jamaica contains four new alkaloids, batzelladines F−I (1-4), that induce the p56lck−CD4 dissociation. Batzelladines F−I were isolated using a bioassay-directed fractionation scheme and were identified by interpretation of spectroscopic data. Batzelladines F, G, and H +...

Full description

Saved in:
Bibliographic Details
Published inJournal of organic chemistry Vol. 62; no. 6; pp. 1814 - 1819
Main Authors Patil, Ashok D, Freyer, Alan J, Taylor, Paul B, Carté, Brad, Zuber, Gary, Johnson, Randall K, Faulkner, D. John
Format Journal Article
LanguageEnglish
Published American Chemical Society 21.03.1997
Online AccessGet full text

Cover

More Information
Summary:The sponge Batzella sp. from Jamaica contains four new alkaloids, batzelladines F−I (1-4), that induce the p56lck−CD4 dissociation. Batzelladines F−I were isolated using a bioassay-directed fractionation scheme and were identified by interpretation of spectroscopic data. Batzelladines F, G, and H + I were active in the p56lck−CD4 dissociation assay at micromolar concentrations.
Bibliography:istex:C6087EBA859DA71F70AD005AE7BC0801DC42B8AA
ark:/67375/TPS-8WVK31Z9-T
Abstract published in Advance ACS Abstracts, March 1, 1997.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo962084t