Symmetry of forward and reverse path populations

In this note, we address formally the issue of symmetry for probabilities of different dynamical pathways in the forward and reverse directions of a conformational transition. Our discussion is based on a decomposition of equilibrium into opposing steady states, and makes clear the conditions necess...

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Bibliographic Details
Main Authors Bhatt, Divesh, Zuckerman, Daniel M
Format Journal Article
LanguageEnglish
Published 11.02.2010
Subjects
Physics - Biological Physics
Physics - Computational Physics
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Summary:In this note, we address formally the issue of symmetry for probabilities of different dynamical pathways in the forward and reverse directions of a conformational transition. Our discussion is based on a decomposition of equilibrium into opposing steady states, and makes clear the conditions necessary for symmetry to apply. From a practical point of view, we also discuss when approximate symmetry is to be expected.
DOI:10.48550/arxiv.1002.2402