Primary Hyperparathyroidism: An Overview

Primary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this pap...

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Published inInternational Journal of Endocrinology Vol. 2011; no. 2011; pp. 25 - 32
Main Authors MacKenzie-Feder, Jessica, Sirrs, Sandra, Anderson, Donald, Sharif, Jibran, Khan, Aneal
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Limiteds 01.01.2011
Hindawi Puplishing Corporation
Hindawi Publishing Corporation
Wiley
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Review
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Summary:Primary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this paper we will review the basic physiology of calcium homeostasis and then consider genetic associations as well as common etiologies and presentations of primary hyperparathyroidism. We will consider emerging trends in detection and measurement of parathyroid hormone as well as available imaging modalities for the parathyroid glands. Surgical indications and approach will be reviewed as well as medical management of primary hyperparathyroidism with bisphosphonates and calcimimetics.
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Academic Editor: Faustino R. Pérez-López
ISSN:1687-8337
1687-8345
DOI:10.1155/2011/251410