Pharmaceutical process development current chemical and engineering challenges.

Pharmaceutical process R&D is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical eng...

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Bibliographic Details
Main Authors Blacker, A. John, Williams, Michael T
Format eBook
LanguageEnglish
Published La Vergne NBN International 2011
Royal Society of Chemistry
Royal Society of Chemistry, The
Edition1
SeriesRSC drug discovery
Subjects
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Summary:Pharmaceutical process R&D is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted the manufacture of pharmaceuticals. In 15 concise chapters the book covers such diverse subjects as route selection and economics, the interface with medicinal chemistry, the impact of green chemistry, safety, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behavior, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation. The book ends with an assessment of future trends and challenges. The book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry.
ISBN:1849731462
9781849733076
1849733074
9781849731461
DOI:10.1039/9781849733076