Omeprazole Antagonizes Virulence and Inflammation in Salmonella enterica-Infected RAW264.7 Cells

• Published in: Antimicrobial Agents and Chemotherapy Vol. 53; no. 6; pp. 2402 - 2409
• Main Authors: PUIAC, Speranta, NEGREA, Aurel, RICHTER-DAHLFORS, Agneta, PLANT, Laura, RHEN, Mikael
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.06.2009; American Society for Microbiology (ASM)
• Subjects: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial diseases; Bacterial diseases of the digestive system and abdomen; Biological and medical sciences; Cell Line; Cell Survival - drug effects; Genomic Islands; Human bacterial diseases; Infectious diseases; Macrolides - pharmacology; Macrophages - microbiology; Mechanisms of Action: Physiological Effects; Medical sciences; Medicin och hälsovetenskap; Mice; Mice, Inbred BALB C; Nitric Oxide - biosynthesis; Nitric Oxide Synthase Type II - antagonists & inhibitors; Omeprazole; Omeprazole - pharmacology; Pharmacology. Drug treatments; Proton Pump Inhibitors; Proton Pump Inhibitors - pharmacology; Salmonella enterica; Salmonella enterica - drug effects; Salmonella enterica - growth & development; Salmonella typhimurium; Vacuoles - drug effects; Vacuoles - metabolism; Virulence; Salmonella; Enzyme; Virulence; H; Enzyme inhibitor; Antiulcer agent; Inflammation; K; Proton pump inhibitor; Infection; Omeprazole; Benzimidazole derivatives; Antisecretory agent; Bacteriosis; Bacteria; exchanging ATPase; Hydrolases; Salmonellosis; Infected cell; Enterobacteriaceae
• ISSN: 0066-4804; 1098-6596; 1098-6596
• DOI: 10.1128/AAC.01483-08

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