Anti-Hepatitis C Virus Activity and Toxicity of Type III Phosphatidylinositol-4-Kinase Beta Inhibitors

• Published in: Antimicrobial Agents and Chemotherapy Vol. 56; no. 10; pp. 5149 - 5156
• Main Authors: LAMARCHE, M. J, BORAWSKI, J, GAO, J, JIANG, X, LIN, K, MCKEEVER, U, PUYANG, X, RAMAN, P, THOHAN, S, TOMMASI, R, WAGNER, K, XIONG, X, BOSE, A, ZABAWA, T, ZHU, S, WIEDMANN, B, CAPACCI-DANIEL, C, COLVIN, R, DENNEHY, M, DING, J, DOBLER, M, DRUMM, J, GAITHER, L. A
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.10.2012
• Subjects: 1-Phosphatidylinositol 4-Kinase; 1-Phosphatidylinositol 4-Kinase - antagonists & inhibitors; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Antiviral Agents - adverse effects; Antiviral Agents - pharmacology; Biological and medical sciences; Bone Marrow Cells - cytology; Bone Marrow Cells - drug effects; Cell Line, Tumor; Cell Proliferation - drug effects; Cell Survival - drug effects; Cells, Cultured; Hepacivirus; Hepacivirus - drug effects; Human viral diseases; Humans; Infectious diseases; Male; Medical sciences; Mice; Pharmacology. Drug treatments; Rats; Rats, Sprague-Dawley; Viral diseases; Viral hepatitis; Enzyme; Toxicity; Transferases; Hepatic disease; Biological activity; Infection; Virus; Phosphatidylinositol; Kinase; Viral disease; Digestive diseases; Inhibitor; Flaviviridae; Hepatitis C virus; Hepacivirus; Viral hepatitis C
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.00946-12

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