Efficacy and Safety of Metronidazole for Pulmonary Multidrug-Resistant Tuberculosis

• Published in: Antimicrobial Agents and Chemotherapy Vol. 57; no. 8; pp. 3903 - 3909
• Main Authors: Carroll, Matthew W., Jeon, Doosoo, Mountz, James M., Lee, Jong Doo, Jeong, Yeon Joo, Zia, Nadeem, Lee, Myungsun, Lee, Jongseok, Via, Laura E., Lee, Soyoung, Eum, Seok-Yong, Lee, Sung-Joong, Goldfeder, Lisa C., Cai, Ying, Jin, Boyoung, Kim, Youngran, Oh, Taegwon, Chen, Ray Y., Dodd, Lori E., Gu, Wenjuan, Dartois, Veronique, Park, Seung-Kyu, Kim, Cheon Tae, Barry, Clifton E., Cho, Sang-Nae
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.08.2013
• Subjects: Adult; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antitubercular Agents; Antitubercular Agents - administration & dosage; Antitubercular Agents - adverse effects; Antitubercular Agents - pharmacokinetics; Antitubercular Agents - therapeutic use; Area Under Curve; Bacterial diseases; Bacterial diseases of the respiratory system; Biological and medical sciences; Clinical Therapeutics; Confidence Intervals; Double-Blind Method; Female; Human bacterial diseases; Humans; Infectious diseases; Lung - microbiology; Lung - pathology; Male; Medical sciences; Metronidazole; Metronidazole - administration & dosage; Metronidazole - adverse effects; Metronidazole - pharmacokinetics; Metronidazole - therapeutic use; Mycobacterium; Mycobacterium tuberculosis - isolation & purification; Peripheral Nervous System Diseases - chemically induced; Pharmacology. Drug treatments; Severity of Illness Index; Sputum - microbiology; Treatment Outcome; Tuberculosis and atypical mycobacterial infections; Tuberculosis, Multidrug-Resistant; Tuberculosis, Multidrug-Resistant - drug therapy; Young Adult; Nitro compound; Imidazole derivatives; Lung disease; Respiratory disease; Toxicity; Treatment efficiency; Pulmonary tuberculosis; Mycobacterial infection; Infection; Antiprotozoal agent; Antifungal agent; Multiple resistance; Bacteriosis; Parasiticide; Metronidazole; Safety
• ISSN: 0066-4804; 1098-6596; 1098-6596
• DOI: 10.1128/aac.00753-13

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