Praise of chromosome "folly" confessions of an untamed molecular structure

When examined carefully at the molecular level, the chromosome turns out to have created its own private world full of tricks, back door exits and novel solutions. This “folly” makes it an untamed innovator. Geneticists have been bewildered for decades. What kind of creature was actually the chromos...

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Bibliographic Details
Main Author ANTONIO, LIMA-DE-FARIA
Format eBook
LanguageEnglish
Published World Scientific Publishing Co. Pte. Ltd 2008
World Scientific Publishing Company
WORLD SCIENTIFIC
WSPC
Subjects
Biotechnology
Cell and Molecular Biology
Chromosomes
Evolution
Evolution Biology
Genetics
Genetics and Genomics
Mutation
Mutation (Biology)
SCIENCE
Selection (Genetics)
Structural Biology
Randomness
Evolution
Magnetism
Selection
Molecular Organization of Chromosome
Gravity
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Summary:When examined carefully at the molecular level, the chromosome turns out to have created its own private world full of tricks, back door exits and novel solutions. This “folly” makes it an untamed innovator. Geneticists have been bewildered for decades. What kind of creature was actually the chromosome? Was it plastic, changing by innumerous rearrangements and mutations all the time; or was it a rigid structure which has preserved its basic organisation and functions since the dawn of the cell? It is this conflicting state that seems to be at the base of its “folly”. Perplexed by this behavior, cell biologists have called it a junkyard and even the ultimate parasite. Moreover, the chromosome has been regarded as a passive cell organelle prone to random mutations and subjected to the mercy of selection.
ISBN:9789812814791
9789812810946
9812814795
9812810943
9789812810953
9812810951
DOI:10.1142/6805