HIV-1 Subtype Is an Independent Predictor of Reverse Transcriptase Mutation K65R in HIV-1 Patients Treated with Combination Antiretroviral Therapy Including Tenofovir

• Published in: Antimicrobial Agents and Chemotherapy Vol. 57; no. 2; pp. 1053 - 1056
• Main Authors: THEYS, K, VERCAUTEREN, J, GROSSMAN, Z, STRUCK, D, VANDAMME, A.-M, ABECASIS, A. B, SNOECK, J, ZAZZI, M, CAMACHO, R. J, TORTI, C, SCHÜLTER, E, CLOTET, B, SÖNNERBORG, A, DE LUCA, A
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.02.2013
• Subjects: Adenine; Adenine - analogs & derivatives; Adenine - therapeutic use; Adult; Anti-HIV Agents; Anti-HIV Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Biological and medical sciences; Cell culture; Drug Resistance, Viral - genetics; Drug Therapy, Combination; Female; Genetic Variation; HIV Infections - drug therapy; HIV Infections - virology; HIV Reverse Transcriptase; HIV Reverse Transcriptase - genetics; HIV-1 - classification; HIV-1 - drug effects; HIV-1 - enzymology; HIV-1 - genetics; Human immunodeficiency virus 1; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Infectious diseases; Male; Medical sciences; Medicin och hälsovetenskap; Middle Aged; Molecular Sequence Data; Organophosphonates; Organophosphonates - therapeutic use; Pharmacology. Drug treatments; Reverse Transcriptase Inhibitors; Reverse Transcriptase Inhibitors - pharmacology; Reverse Transcriptase Inhibitors - therapeutic use; RNA-Directed DNA Polymerase - genetics; Tenofovir; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Antiretroviral agent; RNA-directed DNA polymerase; HIV-1 virus; Reverse transcription; Nucleotide analog; Tenofovir; Reverse transcriptase inhibitor; Nucleoside analog; Antiviral; Immunopathology; Purine nucleotide; Drug combination; Acyclic nucleotide; Typing; Enzyme; Transferases; Enzyme inhibitor; Retroviridae; AIDS; Reverse mutation; Organic phosphonate; Immune deficiency; Lentivirus; Infection; Virus; Nucleotidyltransferases; Chemotherapy; Treatment; Viral disease; Human immunodeficiency virus; Predictive factor; Subtype
• ISSN: 0066-4804; 1098-6596; 1098-6596
• DOI: 10.1128/AAC.01668-12

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