Isolation, Structural Elucidation, and Anti-HIV Activity of Daphnane Diterpenoids from Daphne odora

• Published in: Journal of natural products (Washington, D.C.) Vol. 83; no. 11; pp. 3270 - 3277
• Main Authors: Otsuki, Kouharu, Li, Wei, Miura, Kasumi, Asada, Yoshihisa, Huang, Li, Chen, Chin-Ho, Lee, Kuo-Hsiung, Koike, Kazuo
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society and American Society of Pharmacognosy 25.11.2020; Amer Chemical Soc
• Subjects: antiretroviral properties; Chemistry, Medicinal; Daphne odora; diterpenoids; HIV infections; Life Sciences & Biomedicine; ortho esters; Pharmacology & Pharmacy; Plant Sciences; Science & Technology; spectral analysis; POTENT INHIBITORY-ACTIVITY; ACID; ESTERS

Five new [daphneodorins D–H (1, 5, and 10–12)] and seven known daphnane diterpenoids (2–4 and 6–9) were isolated from Daphne odora. The structures of the new compounds were elucidated by extensive physicochemical and spectroscopic analysis. The isolated compounds were evaluated for their anti-HIV ac...