Pharmacokinetics and Short-Term Safety of 873140, a Novel CCR5 Antagonist, in Healthy Adult Subjects

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Published inAntimicrobial Agents and Chemotherapy Vol. 49; no. 7; pp. 2802 - 2806
Main Authors Adkison, Kimberly K, Shachoy-Clark, Anne, Fang, Lei, Lou, Yu, O'Mara, Kathy, Berrey, M. Michelle, Piscitelli, Stephen C
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.07.2005
Subjects
Adolescent
Adult
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral Agents
Benzoates
Benzoates - administration & dosage
Benzoates - adverse effects
Benzoates - metabolism
Benzoates - pharmacokinetics
Biological and medical sciences
CCR5 Receptor Antagonists
Dose-Response Relationship, Drug
Double-Blind Method
Drug Administration Schedule
Female
Food-Drug Interactions
HIV Fusion Inhibitors
HIV Fusion Inhibitors - administration & dosage
HIV Fusion Inhibitors - adverse effects
HIV Fusion Inhibitors - metabolism
HIV Fusion Inhibitors - pharmacokinetics
Humans
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Piperazines
Spiro Compounds
Spiro Compounds - administration & dosage
Spiro Compounds - adverse effects
Spiro Compounds - metabolism
Spiro Compounds - pharmacokinetics
Short term
Human
CCR5 chemokine receptor
Healthy subject
Toxicity
Adult
Chemokine receptor
Antagonist
CC chemokine
Pharmacokinetics
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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content type line 23
Corresponding author. Mailing address: GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC 27709. Phone: (919) 483-2523. Fax: (919) 315-4529. E-mail: stephen.c.piscitelli@gsk.com.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.49.7.2802-2806.2005