Disposition of Artesunate and Dihydroartemisinin after Administration of Artesunate Suppositories in Children from Papua New Guinea with Uncomplicated Malaria

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Published inAntimicrobial Agents and Chemotherapy Vol. 48; no. 8; pp. 2966 - 2972
Main Authors KARUNAJEEWA, Harin A, ILETT, Kenneth F, DUFALL, Kitiya, KEMIKI, Adedayo, BOCKARIE, Moses, ALPERS, Michael P, BARRETT, P. Hugh, VICINI, Paolo, DAVIS, Timothy M. E
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.08.2004
Subjects
Aging - physiology
alpha-Thalassemia - complications
alpha-Thalassemia - genetics
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antimalarials
Antimalarials - administration & dosage
Antimalarials - pharmacokinetics
Antimalarials - therapeutic use
Artemisinins
Artemisinins - administration & dosage
Artemisinins - metabolism
Artemisinins - pharmacokinetics
Artemisinins - therapeutic use
Artesunate
Biological and medical sciences
Body Weight - physiology
Child
Chromatography, High Pressure Liquid
Female
Genotype
Half-Life
Humans
Malaria
Malaria - drug therapy
Malaria - metabolism
Male
Medical sciences
Models, Statistical
Papua New Guinea
Pharmacology
Pharmacology. Drug treatments
Population
Sesquiterpenes
Sesquiterpenes - administration & dosage
Sesquiterpenes - metabolism
Sesquiterpenes - pharmacokinetics
Sesquiterpenes - therapeutic use
Sex Characteristics
Spectrometry, Mass, Electrospray Ionization
Suppositories
Tissue Distribution
Papua New Guinea
Melanesia
Oceania
Human
Infection
Protozoal disease
Malaria
Artesunate
Parasitosis
Pharmacokinetics
Suppository
Child
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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content type line 23
Corresponding author. Mailing address: University of Western Australia, School of Medicine and Pharmacology, Fremantle Hospital, P.O. Box 480, Fremantle 6959, Australia. Phone: 618 9431 3229. Fax: 618 9431 2977. E-mail: tdavis@cyllene.uwa.edu.au.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.48.8.2966-2972.2004